| | Final 21:08 |  | time |  | gap | L |  | 1. |  Australia | 3:54.44 |  |  | 5 | 1. |  |  | Kaylee McKeown 58.79s, Chelsea Hodges 1:06.68, Emma McKeon 56.59s, Mollie O'Callaghan, 52.38s |  | 2. |  Canada | 3:56.59 |  |  | 4 | 2. |  |  | Kylie Masse 59.01s, Sophie Angus 1:07.66, Maggie Mac Neil 56.59s, Summer McIntosh, 53.33s |  | 3. |  England | 3:59.44 |  |  | 3 | 3. |  |  | Lauren Cox 1:00.72, Molly Renshaw 1:06.61, Laura Stephens 58.96s, Anna Hopkin, 53.15s |  | 4. |  South Africa | 3:59.63 |  |  | 6 | 4. |  |  | Rebecca Meder 1:01.39, Lara van Niekerk 1:05.56, Erin Gallagher 58.88s, Aimee Canny, 53.80s |  | 5. |  Scotland | 4:04.83 |  |  | 2 | 5. |  |  | Katie Shanahan 1:02.27, Kara Hanlon, 1:07.54, Keanna Macinnes 1:00.07, Lucy Hope, 54.95s |  | 6. |  Guernsey | 4:23.37 |  |  | 7 | 6. |  |  | Tatiana Tostevin 1:05.27, Laura le Cras 1:14.82, Orla Rabey 1:02.36, Molly Staples 1:00.92 | 
 | 24 Competitors from 6 Nations. |  | World Record: United States (Regan Smith, Lilly King, Kelsi Dahlia, Simone Manuel 3:50.40 Gwangju, South Korea 28 July 2019 |  | Commonwealth Record: Australia (Kaylee McKeown, Chelsea Hodges, Emma McKeon, Cate Campbell 3:51.60 Tokyo, Japan 1 August 2021 |  | Commonwealth Games Record: Australia (Emily Seebohm, Georgia Bohl, Emma McKeon, Bronte Campbell 3:54.36 Gold Coast, Australia 10 April 2018 | 
 |  |  | 
| 1938: Storey, Frampton, Hinton (ENG) 3x110yd | 
| 1950: Davies, McQuade, Lyons (AUS) 3x110yd | 
| 1954: Gordon, McDowell, Girvan (SCO) 3x110yd | 
| 1958: Grinham, Lonsbrough, Gosden, Wilkinson (ENG) 4x110yd | 
| 1962: Fraser, McGill, Ruygrok, Sergeant (AUS) 4x110yd | 
| 1966: Harris, Gegan, Ludgrove, Sillett (ENG) 4x110yd | 
| 1970: Mabb, Whitfield, Langford, Watson (AUS) | 
| 1974: Amundrud, Stuart, Stenhouse, Cook (CAN) | 
| 1978: Klimpel, Boivin, Stuart, Quirk (CAN) | 
| 1982: Ottenbrite, Gibson, New, MacPherson (CAN) | 
| 1986: Cooper, Fibbens, Hindmarch, Brownsdon (ENG) | 
| 1990: Van Wirdum, Hooiveld, Curry-Kenny, Livingstone (AUS) | 
| 1994: Van Wirdum, Stevenson, Thomas, Riley (AUS) | 
| 1998: Rooney, Denman, Thomas, O'Neill (AUS) | 
| 2002: Calub, Jones, Thomas, Henry (AUS) | 
| 2006: Edington, Jones, Schipper, Lenton (AUS) | 
| 2010: Seebohm, Jones, Schipper, Coutts (AUS) | 
| 2014: Seebohm, Tonks, McKeon, C. Campbell (AUS) | 
| 2018: Seebohm, Bohl, McKeon, B. Campbell (AUS) | 
| 2022: K. McKeown, Hodges, E. McKeon, O'Callaghan (AUS) | 
| . |